Brain biomechanics: Mathematical modelling of the central nervous system compartment

Speaker:

Sivobal Sivaloganathan, U Waterloo

Abstract:

Numerous mathematical models have emerged in the medical literature over the last several decades, attempting to characterize the pressure and volume dynamics of the central nervous system compartment. These models have been used to study he behaviour of this compartment under such pathological clinical conditions as hydrocephalus, head injury and tumour growth. The number of different approaches has led to considerable confusion regarding the validity, accuracy or appropriateness of various models. In this talk, we will review the mathematical basis for these models in a simplified fashion, in the context of hydrocephalus.